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Invitrogen™ MCM8 Polyclonal Antibody
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Catalog No. PIPA599829
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100 μL
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PIPA599829 100 μL
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Catalog No. PIPA599829 Supplier Invitrogen™ Supplier No. PA599829
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MCM8.

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MCM8
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MCM8
Gene Accession No. D3ZVK1, Q9UJA3
Gene Alias 5730432L01Rik; C20orf154; dJ967N21.5; DNA helicase MCM8; DNA replication licensing factor MCM8; MCM8; MCM8 minichromosome maintenance deficient 8; MGC119522; MGC119523; MGC12866; MGC4816; minichromosome maintenance 8; minichromosome maintenance 8 homologous recombination repair factor; minichromosome maintenance complex component 8; minichromosome maintenance deficient 8; minichromosome maintenance deficient 8 (S. cerevisiae); POF10; REC; REC homolog
Gene Symbols MCM8
Host Species Rabbit
Immunogen A synthesized peptide derived from human MCM8(Accession Q9UJA3), corresponding to amino acid residues K734-N784.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 296178, 84515
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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