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Invitrogen™ MCMBP Polyclonal Antibody
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Catalog No. PIPA558410
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100 μL
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PIPA558410 100 μL
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Catalog No. PIPA558410 Supplier Invitrogen™ Supplier No. PA558410
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SPRNTTLERQ TFYCVPVPGE STWVKEAYVN ANQARVSPST SYTPSRHKRS YEDDDDMDLQ PNKQKDQHAG ARQAGSVGGL QWCGEPKRLE TEASTGQ Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 90%.

MEK1 (Mitogen activated protein kinase kinase 1) catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. MEK1 activates ERK1 and ERK2 MAP kinases. Mitogen activated protein kinase kinase 2 (MEK2 or MAPKK2) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1 and 2 and MAPK enzymes by phosphorylating both residues within the threonine/glutamate/tyrosine (TEY) motif in the activation loop. MEK1 and 2 are also activated by dual phosphorylation, which occurs on serine 218 and 222, in the activation loop of the MEK. Threonine 292 of MEK1 is phosphorylated by ERK 2, which serves as a negative feedback loop by suppressing activation of MEK1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MCMBP
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene MCMBP
Gene Accession No. B1H268, Q8R3C0, Q9BTE3
Gene Alias 1110007A13Rik; AU017382; BC025641; C10orf119; cj119; MCM (minichromosome maintenance deficient) binding protein; MCM-binding protein; Mcmbp; MCM-BP; minichromosome maintenance complex binding protein; Mini-chromosome maintenance complex-binding protein; minichromosome maintenance complex-binding protein; RGD1306730
Gene Symbols MCMBP
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MCMBP. Recombinant protein control fragment (Product #RP-97206).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 210711, 309009, 79892
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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