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Invitrogen™ MCP-1 Monoclonal Antibody (24822)
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Catalog No. PIMA191676
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100 μg
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Catalog No. Quantity
PIMA191676 100 μg
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Catalog No. PIMA191676 Supplier Invitrogen™ Supplier No. MA191676
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Description

Mouse Monoclonal Antibody

Neutralization: Human MCP1 is tested for its ability to neutralize the chemoattractant activity of rhMCP1 for human monocytes. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MCP-1
Applications Neutralization, Western Blot
Classification Monoclonal
Clone 24822
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Ccl2
Gene Accession No. P13500
Gene Alias Acidic seminal fluid protein; AI323594; C-C motif chemokine 2; C-C motif chemokine ligand 2; Ccl2; chemokine (C-C motif) ligand 2; GDCF-2; HC11; H-MCP-1; HSMCR30; immediate-early serum-responsive JE protein; immediate-early serum-responsive protein JE; Je; MCAF; Mcp1; MCP-1; MCP1A; MCP-1A; MGC9434; Monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; monocyte chemotactic protein 1A; Monocyte secretory protein JE; monocyte-chemoattractant protein-1 precursor; platelet-derived growth factor-inducible protein JE; RP23-350G1.3; SCYA2; Sigje; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2; small inducible gene JE; small-inducible cytokine A2; SMC-CF
Gene Symbols Ccl2
Host Species Mouse
Immunogen Recombinant human MCP-1/CCL2 expressed in E. Coli.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6347
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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