Invitrogen™ MCP-1 Monoclonal Antibody (E10052), Biotin

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ M2MCP1BI

Catalog No. PIM2MCP1BI

Description

M2MCP1BI targets MCP-1 in ELISA, and WB applications and shows reactivity with Human samples. The M2MCP1BI immunogen is recombinant human MCP-1. M2MCP1BI detects MCP-1 which has a predicted molecular weight of approximately 9 kDa.

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.

Specifications

• Antigen: MCP-1
• Classification: Monoclonal
• Concentration: 0.25 mg/mL
• Formulation: PBS with proprietary preservative; pH 7.2
• Gene Accession No.: P13500
• Gene Symbols: Ccl2
• Immunogen: Recombinant human MCP-1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Western Blot
• Clone: E10052
• Conjugate: Biotin
• Gene: Ccl2
• Gene Alias: Acidic seminal fluid protein; AI323594; C-C motif chemokine 2; C-C motif chemokine ligand 2; Ccl2; chemokine (C-C motif) ligand 2; GDCF-2; HC11; H-MCP-1; HSMCR30; immediate-early serum-responsive JE protein; immediate-early serum-responsive protein JE; Je; MCAF; Mcp1; MCP-1; MCP1A; MCP-1A; MGC9434; Monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; monocyte chemotactic protein 1A; Monocyte secretory protein JE; monocyte-chemoattractant protein-1 precursor; platelet-derived growth factor-inducible protein JE; RP23-350G1.3; SCYA2; Sigje; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2; small inducible gene JE; small-inducible cytokine A2; SMC-CF
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 6347
• Content And Storage: -20°C
• Form: Liquid

Safety and Handling

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