Invitrogen™ MCP-2 Monoclonal Antibody (35509)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA523732

Catalog No. PIMA523732

Description

In ELISAs, this antibody shows less than 0.1% cross-reactivity with recombinant human (rh) CCL15 and rmCCL3. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.

Specifications

• Antigen: MCP-2
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P80075
• Gene Symbols: CCL8
• Immunogen: E. coli-derived recombinant human CCL8/MCP-2.
• Quantity: 500 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Neutralization
• Clone: 35509
• Conjugate: Unconjugated
• Gene: CCL8
• Gene Alias: 1810063B20Rik; AB023418; C-C motif chemokine 8; C-C motif chemokine ligand 8; CCL8; chemokine (C-C motif) ligand 8; HC14; MCP2; MCP-2; MCP-2(6-76); monocyte chemoattractant protein 2; monocyte chemoattractant protein-2; monocyte chemotactic protein 2; SCYA10; SCYA8; small inducible cytokine A8; small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2); small-inducible cytokine A8
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 6355
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized