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Invitrogen™ MCRS1 Polyclonal Antibody
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Catalog No. PIPA5119815
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100 μL
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PIPA5119815 100 μL
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Catalog No. PIPA5119815 Supplier Invitrogen™ Supplier No. PA5119815
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Description

Rabbit Polyclonal Antibody

Positive Control: SH-SY5Y cell lysates, rat large intestine tissue, human liver tissue, human pancreas tissue, mouse testis tissue. Subcellular Location: Nucleus, Nucleolus, Cytoplasm.

Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus (PubMed:11948183). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852). Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity (PubMed:15044100). Binds to G-quadruplex structures in mRNA (PubMed:16571602). Binds to RNA homopolymer poly(G) and poly(U) (PubMed:16571602). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen MCRS1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene MCRS1
Gene Accession No. Q96EZ8, Q99L90
Gene Alias 58 kDa microspherule protein; C78274; cell cycle-regulated factor (78 kDa); cell cycle-regulated factor p78; ICP22BP; INO80 complex subunit J; INO80 complex subunit Q; INO80Q; Mcrs1; MCRS2; Microspherule protein 1; MSP58; nucleolar protein; P78
Gene Symbols MCRS1
Host Species Rabbit
Immunogen Recombinant protein within human MCRS1 aa 1-200.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10445, 300222, 51812
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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