Invitrogen™ MCT2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120845

Catalog No. PIPA5120845

Description

Positive test controls include: DU145, HepG2, HL-60, 293T, rat brain. The target is usually found in the following locations: Cell membrane, Multi-pass membrane protein. Immunogen sequence: TIVECGPVLL GPPLAGKLVD LTGEYKYMYM SCGAIVVAAS VWLLIGNAIN YRLLAKERKE ENARQKTRES EPLSKSKHSE DVNVKVSNAQ SVTSERETNI.

Tissues with few or no mitochondria, such as erythrocytes and tumor cells, depend largely on glycolysis to generate ATP. The major end products of glycolysis, pyruvate and lactate, must be eliminated from these cells to enable continued glycolytic flux and prevent toxic effects. H+/monocarboxylate transporters mediate the transport of lactate and pyruvate. Human MCT2 has a high affinity for the transport of pyruvate.

Specifications

• Antigen: MCT2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC16A7
• Gene Alias: 4921534N07Rik; MCT 2; Mct2; monocarboxylate transporter; Monocarboxylate transporter 2; Slc16a7; solute carrier family 16 (monocarboxylate transporter), member 7; solute carrier family 16 (monocarboxylic acid transporters), member 7; solute carrier family 16 member 7; solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29735, 9194
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.34 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O60669, Q63344
• Gene Symbols: SLC16A7
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 379-478 of human SLC16A7 (NP_0012575511).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov