Invitrogen™ MCT2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552225

Catalog No. PIPA552225

Description

Immunogen sequence: GPNQTTSKSK NKTGKTEDDS SPKKIKTKKS TWEKVNKYLD FS Highest antigen sequence identity to the following orthologs: Mouse - 48%, Rat - 45%.

Tissues with few or no mitochondria, such as erythrocytes and tumor cells, depend largely on glycolysis to generate ATP. The major end products of glycolysis, pyruvate and lactate, must be eliminated from these cells to enable continued glycolytic flux and prevent toxic effects. H+/monocarboxylate transporters mediate the transport of lactate and pyruvate. Human MCT2 has a high affinity for the transport of pyruvate.

Specifications

• Antigen: MCT2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC16A7
• Gene Alias: 4921534N07Rik; MCT 2; Mct2; monocarboxylate transporter; Monocarboxylate transporter 2; Slc16a7; solute carrier family 16 (monocarboxylate transporter), member 7; solute carrier family 16 (monocarboxylic acid transporters), member 7; solute carrier family 16 member 7; solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9194
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O60669
• Gene Symbols: SLC16A7
• Immunogen: Recombinant protein corresponding to Human MCT2. Recombinant protein control fragment (Product #RP-88754).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG