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Invitrogen™ MD-1 Polyclonal Antibody
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Catalog No. 01675205
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100 μg
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Catalog No. Quantity
01-675-205 100 μg
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Catalog No. 01-675-205 Supplier Invitrogen™ Supplier No. PA141586
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Description

Rabbit Polyclonal Antibody

Suggested positive control: Ramos.

MD-1, also known as LY86, is a glycoprotein involved in innate immunity. It is a component of the RP105/MD-1 complex, which is expressed primarily in immune cells like B-cells. MD-1 is structurally similar to MD-2, sharing only 16% sequence identity, yet both are implicated in lipopolysaccharide recognition. The protein contains the ML (MD-2-related lipid-recognition) domain, which is conserved across various species and mediates diverse biological functions by interacting with specific lipids. Structurally, MD-1 is characterized by a beta-rich fold consisting of multiple strands, which is integral to its biological activities. Though MD-1 mainly associates with RP105, its role in lipid recognition suggests functional similarities with proteins such as GM2A and NPC2, implying participation in broader immune signaling pathways.
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Specifications

Antigen MD-1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene LY86
Gene Accession No. O88188, O95711
Gene Alias dJ80N2.1; Ly86; Ly-86; Lymphocyte antigen 86; MD1; MD-1; MD-1, RP105-associated; MMD-1; Protein MD-1; RP1-80N2.1
Gene Symbols LY86
Host Species Rabbit
Immunogen KLH-conjugated synthetic peptide corresponding to amino acids 112-125 of human MD-1.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17084, 9450
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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