Invitrogen™ MD-2 Monoclonal Antibody (18H10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA533351

Catalog No. PIMA533351

Description

Product is supplied at 1 mL (100 μL/mL). Application Notes: This antibody can be used to inhibit LPS binding to MD-2 in vitro. For functional assays, dilutions have to be made according to the amounts of MD-2 to be inactivated.

MD-2 is a gene that encodes a protein involved in the recognition of bacterial lipopolysaccharides (LPS) by the immune system. It is located on chromosome 8 and is part of a larger family of genes that encode for similar proteins. The MD-2 protein forms a complex with Toll-like receptor 4 (TLR4) to recognize and respond to LPS, triggering an immune response. Mutations or variations in the MD-2 gene have been associated with various diseases and conditions, including sepsis and inflammatory disorders.

Specifications

• Antigen: MD-2
• Classification: Monoclonal
• Concentration: 100 μg/mL
• Formulation: PBS with 0.1% BSA and no preservative
• Gene Accession No.: Q9Y6Y9
• Gene Symbols: LY96
• Immunogen: TLR4/MD-2 expressing CHO cells/ chimeric TLR4/MD-2 fusion protein.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Flow Cytometry, Functional Assay
• Clone: 18H10
• Conjugate: Unconjugated
• Gene: LY96
• Gene Alias: Esop1; ESOP-1; LPS co-receptor MD-2; LY96; ly-96; Lymphocyte antigen 96; MD2; MD-2; myeloid differentiation factor-2; myeloid differentiation protein-2; protein MD-2
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 23643
• Content And Storage: 4°C
• Form: Liquid