MD-2 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS2662R

Catalog No. 50-198-4882

Description

Toll-like receptors (TLRs) are evolutionarily conserved patternrecognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. . While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD -1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.

Specifications

• Antigen: MD-2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LY96
• Gene Alias: ESOP1; ESOP-1; LPS co-receptor MD-2; LY96; Ly-96; Lymphocyte antigen 96; MD2; MD-2; myeloid differentiation factor-2; myeloid differentiation protein-2; Protein MD-2
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 23643
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: Q9Y6Y9
• Gene Symbols: LY96
• Immunogen: KLH conjugated synthetic peptide derived from human LY-96.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG