Invitrogen™ MDC1 Monoclonal Antibody (P2B11), FITC

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA545285

Catalog No. PIMA545285

Description

0.5 μg/mL of MA5-45285 was sufficient for detection of MDC1 in 10 μg of HeLa cell lysate by ECL immunoblot analysis. Detects approximately 184kDa. This antibody recognizes MDC1 at and around the N-terminus.

MDC1 participates in the early response to DNA damage. It is thought to be a member of the BRCT (BRCA1 C-terminus) super family of nuclear proteins. It contains an N-terminus forkhead-associated (FHA) motif, two C-terminus BRCT motifs and 13 internal repetitions of a 41 amino acid sequence.

Specifications

• Antigen: MDC1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS, 9.1mM sodium bicarbonate with 640.91mM DMSO, 136.36mM ethanolamine and no preservative; pH 7.4
• Gene Accession No.: Q14676, Q5PSV9, Q7YR40
• Gene Symbols: MDC1
• Immunogen: GST-tagged recombinant protein corresponding to mouse MDC1 at and around the N-terminus.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Bovine, Chimpanzee
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot, Immunocytochemistry
• Clone: P2B11
• Conjugate: FITC
• Gene: MDC1
• Gene Alias: 6820401C03; AA413496; DAAP-285E11.7; DKFZp781A0122; homologue to Drosophila photoreceptor protein calphotin; KIAA0170; MDC1; mediation of DNA damage checkpoint 1; mediator of DNA damage checkpoint 1; mediator of DNA damage checkpoint protein 1; mediator of DNA-damage checkpoint 1; MGC166888; mKIAA0170; NFBD1; nuclear factor with BRCT domains 1
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 240087, 471959, 511168, 9656
• Content And Storage: 4°C, store in dark
• Form: Liquid

Safety and Handling

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