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Mdc1/Nfbd1 Rabbit anti-Mouse, Polyclonal, Bethyl Laboratories

Catalog No. 501568831
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50-156-8831 10 μL
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Catalog No. 50-156-8831 Supplier Bethyl Laboratories, Inc Supplier No. A304843AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.

Specifications

Antigen Mdc1/Nfbd1
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Mdc1
Gene Accession No. Q5PSV9
Gene Alias DAAP-285E11.7, DKFZp781A0122, KIAA0170, MGC166888, NFBD1
Gene Symbols Mdc1
Host Species Rabbit
Immunogen Between 900 and 950
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 240087
Target Species Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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