Invitrogen™ MDC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597022

Catalog No. PIPA597022

Description

Immunogen sequence: MEDTQAIDWD VEEEEETEQS SESLRCNVEP VGRLHIFSGA HGPEKDFPLH LGKNVVGRMP DCSVALPFPS ISKQHAEIEI LAWDKAPILR DCGSLNGTQI LRPPKVLSPG VSHRLRDQEL ILFADLLCQY HRLDVSLPFV SRGPLTVEET PRVQGETQPQ RLLLAEDSEE EVDFLSERRM VKKSRTTSSS VIVPESDEEG HSPVLGGLGP PFAFNLNSDT DVEEGQQPAT EEASSAARRG ATVEAKQSEA EVVTEIQLEK DQPLVKERDN DTKVKRGAGN GVVPAGVILE RSQPPGEDSD TDVDDDSRPP GRPAEVHLER AQPFGFIDSD TDAEEERIPA TPVVIPMKKR; Positive Samples: Jurkat, LO2; Cellular Location: Chromosome, Nucleus.

MDC1 participates in the early response to DNA damage. It is thought to be a member of the BRCT (BRCA1 C-terminus) super family of nuclear proteins. It contains an N-terminus forkhead-associated (FHA) motif, two C-terminus BRCT motifs and 13 internal repetitions of a 41 amino acid sequence.

Specifications

• Antigen: MDC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MDC1
• Gene Alias: 6820401C03; AA413496; DAAP-285E11.7; DKFZp781A0122; homologue to Drosophila photoreceptor protein calphotin; KIAA0170; MDC1; mediation of DNA damage checkpoint 1; mediator of DNA damage checkpoint 1; mediator of DNA damage checkpoint protein 1; mediator of DNA-damage checkpoint 1; MGC166888; mKIAA0170; NFBD1; nuclear factor with BRCT domains 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9656
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.28 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q14676
• Gene Symbols: MDC1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human MDC1 (NP_0554562).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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