Invitrogen™ MDFI Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA562108

Catalog No. PIPA562108

Description

Immunogen sequence: LPNDSGHPSE LGGTRRAGNG ALGGPKAHRK LQTHPSLASQ GSKKSKSSSK STTSQIPLQA QEDCC Highest antigen sequence identity to the following orthologs: Mouse - 67%, Rat - 72%.

MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation.

Specifications

• Antigen: MDFI
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mdfi
• Gene Alias: I-mf; I-mfa; inhibitor of MyoD family a; MDFI; MyoD family inhibitor; myogenic repressor I-mf; RGD1560271
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4188
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q99750
• Gene Symbols: Mdfi
• Immunogen: Recombinant protein corresponding to Human MDFI. Recombinant protein control fragment (Product #RP-101208).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG