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Invitrogen™ MDFI Polyclonal Antibody
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Catalog No. PIPA5142482
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100 μg
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Catalog No. Quantity
PIPA5142482 100 μg
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Catalog No. PIPA5142482 Supplier Invitrogen™ Supplier No. PA5142482
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Description

Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.

MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MDFI
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Mdfi
Gene Accession No. Q99750
Gene Alias I-mf; I-mfa; inhibitor of MyoD family a; MDFI; MyoD family inhibitor; myogenic repressor I-mf; RGD1560271
Gene Symbols Mdfi
Host Species Goat
Immunogen Peptide with sequence C-SKSTTSQIPLQAQED (aa 148-162).
Purification Method Ammonium Sulfate Precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4188
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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