Invitrogen™ MDFI Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101683

Catalog No. PIPA5101683

Description

Antibody detects endogenous levels of total MDFI.

MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation.

Specifications

• Antigen: MDFI
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mdfi
• Gene Alias: I-mf; I-mfa; inhibitor of MyoD family a; MDFI; MyoD family inhibitor; myogenic repressor I-mf; RGD1560271
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17240, 4188, 501097
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P70331, Q99750
• Gene Symbols: Mdfi
• Immunogen: A synthesized peptide derived from human MDFI(Accession Q99750), corresponding to amino acid residues N102-T152.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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