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Description
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. [provided by RefSeq]
Specifications
Specifications
| Antigen | MDFI |
| Applications | Immunofluorescence, Immunohistochemistry (PFA fixed) |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | MDFI polyclonal antibody raised against recombinant human MDFI. |
| Dilution | Immunofluorescence (1-4 ug/mL) Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide) |
| Gene Alias | I-MF/I-mfa |
| Gene Symbols | MDFI |
| Host Species | Rabbit |
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