MDFI Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS18743R

Catalog No. 50-198-9862

Description

MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation.

Specifications

• Antigen: MDFI
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mdfi
• Gene Alias: I-MF; I-mfa; inhibitor of MyoD family a; MDFI; MyoD family inhibitor; Myogenic repressor I-mf; RGD1560271
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 4188
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
• Concentration: 1 μg/mL
• Formulation: TBS with 1% BSA, 50% glycerol and 0.03% Proclin 300; pH
• Gene Accession No.: Q99750
• Gene Symbols: Mdfi
• Immunogen: KLH conjugated synthetic peptide derived from human MDFI.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG