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MDFI Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501989862
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100 μL
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50-198-9862 100 μL
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Catalog No. 50-198-9862 Supplier Bioss Supplier No. BS18743R
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Description

Rabbit Polyclonal Antibody

MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation.

Specifications

Antigen MDFI
Applications Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation TBS with 1% BSA, 50% glycerol and 0.03% Proclin 300; pH
Gene Mdfi
Gene Accession No. Q99750
Gene Alias I-MF; I-mfa; inhibitor of MyoD family a; MDFI; MyoD family inhibitor; Myogenic repressor I-mf; RGD1560271
Gene Symbols Mdfi
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human MDFI.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4188
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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