Invitrogen™ MDFIC Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550706

Catalog No. PA550706

Description

The antibody detects endogenous levels of total MDFIC protein.

MDFIC is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization; p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain.This gene product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization; p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain.

Specifications

• Antigen: MDFIC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MDFIC
• Gene Alias: HIC; I-mfa domain-containing protein; MDFIC; MDFIC (HGNC:28870); MyoD family inhibitor domain containing; MyoD family inhibitor domain containing protein; myoD family inhibitor domain-containing protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29969
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1.7 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q9P1T7
• Gene Symbols: MDFIC
• Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human MyoD family inhibitor domain containing.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG