MDM4 Mouse anti-Human, Clone: OTI1D11, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF505722

Catalog No. 50-166-3866

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.

Specifications

• Antigen: MDM4
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: MDM4
• Gene Alias: HDMX, MDMX, MRP1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4194
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1D11
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: O15151
• Gene Symbols: MDM4
• Immunogen: Full length human recombit protein of human MDM4 produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a