Invitrogen™ ME1 Monoclonal Antibody (3I6)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA523524

Catalog No. MA523524

Description

Recommended positive controls: 293T, A431, and HeLa cells. Predicted reactivity: Mouse (91%), Rat (91%), Chicken (80%), Sheep (92%), Bovine (91%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ME1 encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.

Specifications

• Antigen: ME1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P06801, P48163
• Gene Symbols: Me1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human ME1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
• Clone: 3I6
• Conjugate: Unconjugated
• Gene: Me1
• Gene Alias: cytosolic malic enzyme 1; D9Ertd267e; HUMNDME; malate dehydrogenase; malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+); malate dehydrogenase decarboxylase (NADP+); malic enzyme; malic enzyme 1; malic enzyme 1, NADP(+)-dependent, cytoplasmic (cytosolic, soluble); malic enzyme 1, NADP(+)-dependent, cytosolic; malic enzyme 1, soluble; Malic enzyme, cytoplasmic; malic enzyme, supernatant; Mdh-1; ME1; MES; Mod1; Mod-1; NADP-dependent malic enzyme; NADP-dependent malic enzyme-like protein; NADP-ME; pyruvic-malic carboxylase
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 17436, 4199
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid