Invitrogen™ ME2 Monoclonal Antibody (970CT2.1.1.2)

Catalog No.	Quantity
PIMA537745	200 μL

Catalog No. PIMA537745 Supplier Invitrogen™ Supplier No. MA537745

Description

Mouse Monoclonal Antibody

ME2 Monoclonal Antibody for Western Blot, IHC (P)

ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.

Specifications

• Antigen: ME2
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 970CT2.1.1.2
• Concentration: 0.4 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene: Me2
• Gene Accession No.: P23368, Q99KE1
• Gene Alias: AW120568; D030040L20Rik; malate dehydrogenase; malate dehydrogenase (oxaloacetate-decarboxylating); malic enzyme 2; malic enzyme 2, NAD(+)-dependent, mitochondrial; Me2; NAD-dependent malic enzyme, mitochondrial; NAD-ME; ODS1; pyruvic-malic carboxylase
• Gene Symbols: Me2
• Host Species: Mouse
• Immunogen: KLH conjugated synthetic peptide between 522-556 amino acids from the C-terminal region of human ME2.
• Purification Method: Protein G
• Quantity: 200 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 107029, 4200
• Target Species: Human, Mouse
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1 κ

Safety and Handling

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