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Invitrogen™ ME2 Polyclonal Antibody
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Catalog No. PIPA538007
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100 μg
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Catalog No. Quantity
PIPA538007 100 μg
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Catalog No. PIPA538007 Supplier Invitrogen™ Supplier No. PA538007
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Description

Rabbit Polyclonal Antibody

A recommended positive control is human spleen tissue lysate. At least two isoforms of ME2 are known to exist; this antibody will detect both isoforms. ME2 antibody is not expected to cross-react with ME1.

ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ME2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Me2
Gene Accession No. P23368
Gene Alias AW120568; D030040L20Rik; malate dehydrogenase; malate dehydrogenase (oxaloacetate-decarboxylating); malic enzyme 2; malic enzyme 2, NAD(+)-dependent, mitochondrial; Me2; NAD-dependent malic enzyme, mitochondrial; NAD-ME; ODS1; pyruvic-malic carboxylase
Gene Symbols Me2
Host Species Rabbit
Immunogen 17 amino acid peptide near the center of human ME2.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4200
Target Species Human
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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