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Invitrogen™ ME2 Polyclonal Antibody
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Catalog No. PIPA5115562
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PIPA5115562 100 μL
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Catalog No. PIPA5115562 Supplier Invitrogen™ Supplier No. PA5115562
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ME2.

ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ME2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene Me2
Gene Accession No. P23368, Q99KE1
Gene Alias AW120568; D030040L20Rik; malate dehydrogenase; malate dehydrogenase (oxaloacetate-decarboxylating); malic enzyme 2; malic enzyme 2, NAD(+)-dependent, mitochondrial; Me2; NAD-dependent malic enzyme, mitochondrial; NAD-ME; ODS1; pyruvic-malic carboxylase
Gene Symbols Me2
Host Species Rabbit
Immunogen A synthesized peptide derived from human ME2(Accession P23368), corresponding to amino acid residues P200-T250.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 107029, 4200
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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