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Invitrogen™ ME2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552621

Catalog No. PIPA552621


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Description

Description

Immunogen sequence: KVISKPISEH KILFLGAGEA ALGIANLIVM SMVENGLSEQ EAQKKIWMFD KYGLLVKGRK AKIDSYQEPF THSAPESIPD TFEDAVNILK PSTIIGVAGA GRLFTPDVIR AMASINERPV IFALSNPTA Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 80%.

ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

ME2
Polyclonal
Unconjugated
Me2
AW120568; D030040L20Rik; malate dehydrogenase; malate dehydrogenase (oxaloacetate-decarboxylating); malic enzyme 2; malic enzyme 2, NAD(+)-dependent, mitochondrial; Me2; NAD-dependent malic enzyme, mitochondrial; NAD-ME; ODS1; pyruvic-malic carboxylase
Rabbit
Antigen affinity chromatography
RUO
4200
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
P23368
Me2
Recombinant protein corresponding to Human ME2. Recombinant protein control fragment (Product #RP-88954).
100 μL
Primary
Human
Antibody
IgG
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