Invitrogen™ MEAF6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA540704

Catalog No. PIPA540704

Description

Peptide sequence: HNKAAPPQIP DTRRELAELV KRKQELAETL ANLERQIYAF EGSYLEDTQM Sequence homology: Cow: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 92%.

The screening of cDNA expression libraries from human tumors with serum antibody (SEREX) has proven to be a powerful method for identifying the repertoire of tumor antigens recognized by the immune system of cancer patients, referred to as the cancer immunome. In this regard, cancer/testis (CT) antigens are of particular interest because of their immunogenicity and restricted expression patterns. Synovial sarcomas are striking with regard to CT antigen expression, however, highly expressed in sarcoma, CT antigens do not induce frequent humoral immune responses in sarcoma patients. Sera from two patients were used to immunoscreen cDNA libraries from two synovial sarcoma cell lines and normal testis, resulting in the identification of 113 distinct antigens.

Specifications

• Antigen: MEAF6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MEAF6
• Gene Alias: 2310005N01Rik; 2810036M01Rik; C1orf149; C3H1orf149; CDABP0189; CENP-28; centromere protein 28; chromatin modification-related protein MEAF6; chromatin modification-related protein MEAF6-like; EAF6; Esa1-associated factor 6 homolog; Esa1p-associated factor 6 homolog; fj63g06; FLJ11730; meaf6; MYST/Esa1 associated factor 6; MYST/Esa1-associated factor 6; NY-SAR-91; Protein EAF6 homolog; RGD1310440; RP3-423B22.2; sarcoma antigen NY-SAR-91; wu:fj63g06; zgc:100869
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64769
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9HAF1
• Gene Symbols: MEAF6
• Immunogen: Synthetic peptide directed towards the N-terminal of human FLJ11730 (aa 4-53).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov