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Invitrogen™ MECOM Polyclonal Antibody
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Catalog No. PIPA5115607
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PIPA5115607 100 μL
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Catalog No. PIPA5115607 Supplier Invitrogen™ Supplier No. PA5115607
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Myelodysplasia Syndrome 1.

EVI1 (MECOM) is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, cell differentiation, and proliferation. It can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. The EVI1 gene can undergo translocation with the AML1 gene, resulting in overexpression of the EVI1 gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MECOM
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene MECOM
Gene Accession No. Q03112
Gene Alias AML1-EVI-1; AML1-EVI-1 fusion protein; D630039M04Rik; ecotropic viral integration site 1; ecotropic virus integration site 1 protein; Ecotropic virus integration site 1 protein homolog; EVI1; Evi-1; Histone-lysine N-methyltransferase MECOM; Jbo; Mds; MDS1; MDS1 and EVI1 complex locus; MDS1 and EVI1 complex locus protein; MDS1 and EVI1 complex locus protein EVI1; MDS1 and EVI1 complex locus protein MDS1; Mds1-Evi1; Mecom; MGC163392; MGC97004; myelodysplasia syndrome 1 homolog; Myelodysplasia syndrome 1 protein; Myelodysplasia syndrome 1 protein homolog; myelodysplasia syndrome-associated protein 1; oncogene EVI1; OTTHUMP00000213163; OTTHUMP00000213164; OTTHUMP00000213165; OTTHUMP00000213187; OTTHUMP00000213192; PR domain 3; PRDM3; RUSAT2; zinc finger protein Evi1; Znfpr1b1
Gene Symbols MECOM
Host Species Rabbit
Immunogen A synthesized peptide derived from human MECOM(Accession Q03112), corresponding to amino acid residues I100-Y150.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2122
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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