Invitrogen™ MECP2 Polyclonal Antibody

Catalog No.	Quantity
50-255-0797	50 μg

Catalog No. 50-255-0797 Supplier Invitrogen™ Supplier No. 491029

Description

Rabbit Polyclonal Antibody

MECP2 Polyclonal Antibody for Western Blot, IP, ChIP, ELISA, RIP

MECP2 belongs to a family of nuclear proteins (including MBD1, MBD2, MBD3 and MBD4) that have a methyl-CpG binding domain. MECP2 is capable of binding specifically to methylated DNA. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. MECP2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.

Specifications

• Antigen: MECP2
• Applications: ChIP Assay, ELISA, Immunoprecipitation, Western Blot, RNA Immunoprecipitation
• Classification: Polyclonal
• Concentration: Conc. Not Determined
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% ProClin 300, 0.05% sodium azide
• Gene: Mecp2
• Gene Accession No.: P51608
• Gene Alias: 1500041B07Rik; AUTSX3; D630021H01Rik; DKFZp686A24160; Mbd5; MECP2; MeCp-2 protein; methyl CpG binding protein 2; methyl-CpG binding protein 2; methyl-CpG-binding protein 2; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT; testis tissue sperm-binding protein Li 41a; WBP10
• Gene Symbols: Mecp2
• Host Species: Rabbit
• Immunogen: Raised against the C-term of human MECP2.
• Purification Method: Affinity chromatography
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4204
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG