Invitrogen™ MED10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578599

Catalog No. PIPA578599

Description

Positive Control: 293T, 293T nuclear extract Predicted Reactivity: Mouse (100%), Rat (100%), Zebrafish (85%), Xenopus laevis (92%), Rhesus Monkey (98%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

MED10 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Specifications

• Antigen: MED10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MED10
• Gene Alias: AA959813; AI385605; C78613; D13Wsu50e; L6; Med10; Mediator complex subunit 10; mediator of RNA polymerase II transcription subunit 10; mediator of RNA polymerase II transcription, subunit 10; mediator of RNA polymerase II transcription, subunit 10 homolog (NUT2, S. cerevisiae); NUT2; RGD1310128; Transformation-related gene 17 protein; transformation-related gene 20 protein; TRG17; TRG-17; TRG20; TRG-20
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84246
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1.03 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q9BTT4
• Gene Symbols: MED10
• Immunogen: Recombinant protein encompassing a sequence within the center region of human MED10. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov