Invitrogen™ MED12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550718

Catalog No. PA550718

Description

The antibody detects endogenous levels of total MED12 / TRAP230 protein.

The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C.

Specifications

• Antigen: MED12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Med12
• Gene Alias: 230kDa; activator-recruited cofactor 240 kDa component; ARC240; CAG repeat protein 45; CAGH45; FGS1; HOPA; human opposite paired; Kiaa0192; Med12; MED12S; Mediator complex subunit 12; mediator of RNA polymerase II transcription subunit 12; mediator of RNA polymerase II transcription, subunit 12 homolog; Mopa; OHDOX; OKS; OPA1; OPA-1; OPA-containing protein; OPA-containing protein 1; putative mediator subunit 12; thyroid hormone receptor-associated protein complex 230 kDa component; thyroid hormone receptor-associated protein, 230 kDa subunit; TNRC11; TRAP230; trinucleotide repeat containing 11 (THR-associated protein); trinucleotide repeat containing 11 (THR-associated protein, 230 kDa subunit); trinucleotide repeat-containing gene 11 protein
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 59024, 9968
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1.7 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: A2AGH6, Q93074
• Gene Symbols: Med12
• Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human mediator complex subunit 12.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG