Invitrogen™ MED12L Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA557827

Catalog No. PIPA557827

Description

Immunogen sequence: LSVTASTRPR SPVGENADEH YSKDHDVKME IFSPMPGESC ENANTSLGRR MSVNCEKLVK REKPRELIFP SNYDLL Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 84%.

MED12L, also named as KIAA1635, TNRC11L, TRALP and TRALPUSH, belongs to the Mediator complex subunit 12 family. MED12L may be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. MED12L is a mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. MED12L is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Specifications

• Antigen: MED12L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MED12L
• Gene Alias: A130035F20; A630079M02; AU044581; KIAA1635; Kiaa3007; MED12L; mediator complex subunit 12 like; mediator complex subunit 12-like; mediator complex subunit 12-like protein; Mediator of RNA polymerase II transcription subunit 12-like protein; mediator of RNA polymerase II transcription, subunit 12 homolog-like; no opposite paired repeat protein; NOPAR; PRO0314; RGD1304617; thyroid hormone receptor-associated-like protein; TNRC11L; TRALP; TRALPUSH; trinucleotide repeat-containing gene 11 protein-like
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116931
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q86YW9
• Gene Symbols: MED12L
• Immunogen: Recombinant protein corresponding to Human MED12L. Recombinant protein control fragment (Product #RP-96365).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG