Invitrogen™ MED27 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA540771

Catalog No. PIPA540771

Description

Peptide sequence: LSRPNGTSAM LLVTLGKVLK VIVVMRSLFI DRTIVKGYNE NVYTEDGKLD Sequence homology: Cow: 100%; Dog: 85%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 85%; Rat: 100%.

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.

Specifications

• Antigen: MED27
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MED27
• Gene Alias: 1500015J03Rik; 2310042P07Rik; AA682045; cofactor required for Sp1 transcriptional activation subunit 8; cofactor required for Sp1 transcriptional activation, subunit 8; cofactor required for Sp1 transcriptional activation, subunit 8, 34kDa; CRAP34; CRSP complex subunit 8; CRSP34; CRSP8; D2Ertd434e; LOC525389 protein; MED27; MED3; mediator complex subunit 27; Mediator of RNA polymerase II transcription subunit 27; MGC11274; p37 TRAP/SMCC/PC2 subunit; RGD1564993; transcriptional coactivator CRSP34; transcriptional co-activator CRSP8 homolog; TRAP37
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9442
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q6P2C8
• Gene Symbols: MED27
• Immunogen: Synthetic peptide directed towards the middle region of human MED27.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov