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Invitrogen™ MED6 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA540846
Description
Peptide sequence: LLLDLRQKFP PKFVQLKPGE KPVPVDQTKK EAEPIPETVK PEEKETTKNV Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 93%; Rat: 93%.
MED6 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. And mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Specifications
MED6 | |
Polyclonal | |
Unconjugated | |
Med6 | |
1500012F11Rik; Activator-recruited cofactor 33 kDa component; ARC33; AU019660; AV213303; CTD-2540L5.5; hMed6; hypothetical protein LOC505293; MED6; Mediator complex subunit 6; mediator of RNA polymerase II transcriptio subunit 6-like protein; mediator of RNA polymerase II transcription subunit 6; mediator of RNA polymerase II transcription, subunit 6 homolog; NY-REN-28; Renal carcinoma antigen NY-REN-28 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
10001 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ChIP Assay, Western Blot | |
0.5 mg/mL | |
PBS with 2% sucrose and 0.09% sodium azide | |
O75586 | |
Med6 | |
Synthetic peptide directed towards the middle region of human MED6. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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