Invitrogen™ MED6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565079

Catalog No. PIPA565079

Description

Immunogen sequence: NSGSVLDYFSE RSNPFYDRTC NNEVVKMQRL TLEHLNQMVG IEYILLHAQE PILFIIRKQQ RQSPAQVIPL ADYYIIAGVI YQAPDLGSVI NSRVLTAVHG IQSAFDEAMS YCRYHPSKGY WWHFKDHEEQ DKVRPKAKRK EEPSSI Highest antigen sequence identity to the following orthologs - mouse 99%, rat 99%.

MED6 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. And mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Specifications

• Antigen: MED6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Med6
• Gene Alias: 1500012F11Rik; Activator-recruited cofactor 33 kDa component; ARC33; AU019660; AV213303; CTD-2540L5.5; hMed6; hypothetical protein LOC505293; MED6; Mediator complex subunit 6; mediator of RNA polymerase II transcriptio subunit 6-like protein; mediator of RNA polymerase II transcription subunit 6; mediator of RNA polymerase II transcription, subunit 6 homolog; NY-REN-28; Renal carcinoma antigen NY-REN-28
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10001
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O75586
• Gene Symbols: Med6
• Immunogen: Recombinant Human MED6. Recombinant protein control fragment (Product #RP-104618).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov