Invitrogen™ MED9 Polyclonal Antibody

Catalog No.	Quantity
PIPA5103920	100 μL

Catalog No. PIPA5103920

Supplier: Invitrogen™ PA5103920

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MED9.

In mammalian cells, transcription is regulated in part by high molecular weight co-activating complexes that mediate signals between transcriptional activators and RNA polymerase II (Pol II). The mediator complex is one such multi-protein structure that functions as a bridge between regulatory proteins and Pol II, thereby regulating Pol II-dependent transcription. Med9 (mediator complex subunit 9), also known as MED25, is a 146 amino acid nuclear protein and component of the mediator complex. Med9 directly interacts with Med4 and is encoded by a gene that maps to human chromosome 17p11.2. Chromosome 17 comprises over 2.5% of the human genome, encodes over 1,200 genes and is associated with two key tumor suppressor genes, namely, p53 and BRCA1.

Specifications

• Antigen: MED9
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: Med9
• Gene Accession No.: Q8VCS6, Q9NWA0
• Gene Alias: BC019367; Med25; Med9; Mediator complex subunit 9; mediator of RNA polymerase II transcription subunit 9; mediator of RNA polymerase II transcription, subunit 9 homolog; mediator subunit 25; RGD1563669
• Gene Symbols: Med9
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human MED9(Accession Q9NWA0), corresponding to amino acid residues K99-E146.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 192191, 55090
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov