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MEF2A Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Catalog No. 501565391
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50-156-5391 100 μL
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Catalog No. 50-156-5391 Supplier Bethyl Laboratories, Inc Supplier No. A303531A
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Chicken and Orangutan

The myocyte enhancer factor-2 (MEF-2) family of transcription factors associated with co-repessors or co-activators to regulate development and function of T cells, neuronal cells and muscle cells. Four family members arise from alternatively spliced transcripts, termed MEF-2A, -2B, -2C and -2D. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression.

Specifications

Antigen MEF2A
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene MEF2A
Gene Accession No. Q02078, Q60929
Gene Alias myocyte enhancer factors-2
Gene Symbols MEF2A
Host Species Rabbit
Immunogen Between 175 and 225
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17258, 4205
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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