Invitrogen™ MEF2B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA575240

Catalog No. PIPA575240

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

The myocyte enhancer factor-2 (MEF-2) family of transcription factors associated with co-repessors or co-activators to regulate development and function of T cells, neuronal cells and muscle cells. Four family members arise from alternatively spliced transcripts, termed MEF-2A, -2B, -2C and -2D. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression.

Specifications

• Antigen: MEF2B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MEF2B
• Gene Alias: 2310045N01Rik; AI451606; BLOC-1-related complex subunit 8; Borcs8; BORCS8-MEF2B; BORCS8-MEF2B readthrough; LOC729991-MEF2B; LOC729991-MEF2B readthrough; MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B); MEF2B; MEF2B neighbor gene protein homolog; Mef2bnb; MEF2BNB-MEF2B; MEF2BNB-MEF2B readthrough; myocyte enhancer factor 2B; myocyte-specific enhancer factor 2B; protein MEF2BNB; RIKEN cDNA 2310045N01 gene; RSRFR2; Serum response factor-like protein 2; XMEF2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100271849, 17259, 498607
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide; pH 7.2
• Gene Accession No.: O55087, Q02080
• Gene Symbols: MEF2B
• Immunogen: Synthetic peptide corresponding to amino acids 80-120 of Human MEF2B.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG