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Megestrol Acetate, Tocris Bioscience™
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Catalog No. 628550
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Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Synthetic progesterone analog

Synthetic progesterone analog. Dose-dependently inhibits growth of HepG2 cells (IC50 = 260 μM) in vitro and in vivo and reduces tumor volume. High dosages improve weight gain in tumor-bearing nude mice. Orally bioavailable.

Chemical Identifiers

CAS 595-33-5
Molecular Formula C24H32O4
Molecular Weight (g/mol) 384.516
InChI Key RQZAXGRLVPAYTJ-GQFGMJRRSA-N
Synonym megestrol acetate, niagestin, megace es, megestryl acetate, megace, megeron, ovaban, ovarid, pallace, magestin
PubChem CID 11683
IUPAC Name [(8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
SMILES CC1=CC2C(CCC3(C2CCC3(C(=O)C)OC(=O)C)C)C4(C1=CC(=O)CC4)C

Specifications

Linear Formula C24H32O4
Quantity 50 mg
Solubility Information Soluble to 50mM in DMSO and to 20mM in ethanol
Formula Weight 384.51
Percent Purity >98%
Physical Form Solid
Chemical Name or Material 17-(Acetyloxy)-6-methylpregna-4,6-diene-3,20-dione

Safety and Handling

Recommended Storage Store at Room Temperature
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