Invitrogen™ MEIOB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA568422

Catalog No. PIPA568422

Description

MEIOB Polyclonal Antibody for IHC (P)

Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro.

Specifications

• Antigen: MEIOB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MEIOB
• Gene Alias: 4930528F23Rik; C16orf73; C6H16orf73; gs129; Meiob; meiosis specific with OB domains; meiosis specific with OB-fold; meiosis-specific with OB domain-containing protein; MLZ-675; Protein expressed in male leptotene and zygotene spermatocytes 675
• Host Species: Rabbit
• Purification Method: affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 254528
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.7 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q8N635
• Gene Symbols: MEIOB
• Immunogen: Synthetic protein corresponding to residues near the C terminal of human MEIOB.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG