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Invitrogen™ MEIOB Polyclonal Antibody
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Catalog No. PIPA568422
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100 μL
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PIPA568422 100 μL
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Catalog No. PIPA568422 Supplier Invitrogen™ Supplier No. PA568422
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Description

Rabbit Polyclonal Antibody

MEIOB Polyclonal Antibody for IHC (P)

Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MEIOB
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.7 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene MEIOB
Gene Accession No. Q8N635
Gene Alias 4930528F23Rik; C16orf73; C6H16orf73; gs129; Meiob; meiosis specific with OB domains; meiosis specific with OB-fold; meiosis-specific with OB domain-containing protein; MLZ-675; Protein expressed in male leptotene and zygotene spermatocytes 675
Gene Symbols MEIOB
Host Species Rabbit
Immunogen Synthetic protein corresponding to residues near the C terminal of human MEIOB.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 254528
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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