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MEK1 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA516556
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PIPA516556 500 μL
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Catalog No. PIPA516556 Supplier Thermo Scientific Supplier No. PA516556

Description

Rabbit Polyclonal Antibody

PA5-16556 targets MEK-1 in WB applications and shows reactivity with mouse, Rat, Xn, and Human samples. The PA5-16556 immunogen is a synthetic peptide derived from the N-terminus of human Mek1 protein.

MAP2K1 (MEK1) kinase is a dual-specificity protein kinase that functions in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation. MAP2K1 is activated by a wide variety of growth factors and cytokines and also by membrane-dependent depolarization and calcium influx. Mek1 is activated by phosphorylation of serine 218 and 222 residues by Raf1. It is known to be involved in the signaling during stress activate response, apoptosis and proliferative induction by cytokines. Mutations in the gene can lead to cardiofaciocutaneous syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MEK1
Applications Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Map2k1
Gene Accession No. P31938, Q01986, Q02750, Q05116
Gene Alias CFC3; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; EC 2.7.12.2; ERK activator kinase 1; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2); MAP kinase/Erk kinase 1; Map2k1; map2k1.L; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; Mek1; MEK2; mek-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1 L homeolog; MKK (Thr292); MKK (Thr386); MKK1; MKK2; MP2K1; Prkmk1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); XELAEV_18018447mg
Gene Symbols Map2k1, map2k1.L
Host Species Rabbit
Immunogen A synthetic peptide derived from the N-terminus of human Mek1 protein
Purification Method Protein A
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 170851, 26395, 379991, 5604
Target Species Human, Mouse, Rat, X. laevis
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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