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Invitrogen™ MEK2 Polyclonal Antibody
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Catalog No. PIPA5143114
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100 μg
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PIPA5143114 100 μg
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Catalog No. PIPA5143114 Supplier Invitrogen™ Supplier No. PA5143114
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Description

Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

MAP2K2 (MEK2) is a dual specificity serine/threonine kinase that is known to play a critical role in mitogen growth factor signal transduction. Mitogen activated protein kinase 2 (MEK2 or MAPKK2) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1 and 2 and MAPK enzymes by phosphorylating both residues within the threonine/glutamate/tyrosine (TEY) motif in the activation loop. MEK1 and 2 are also activated by dual phosphorylation, which occurs on serine 218 and 222, in the activation loop of the MEK. Threonine 292 of MEK1 is phosphorylated by ERK 2, which serves as a negative feedback loop by suppressing activation of MEK1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MEK2
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene MAP2K2
Gene Accession No. P36507
Gene Alias AA589381; CFC4; Dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 2; ERK kinase 2; FLJ26075; MAP kinase kinase 2; MAP kinase/Erk kinase; MAP2K1; MAP2K2; MAPK; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK 2; MAPKK2; MEK 1; MEK 2; MEK-1; Mek2; MEK-2; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; MK2; MKK1; Mkk2; OTTHUMP00000165827; PRKMK1; PRKMK2; protein kinase, mitogen activated, kinase 2, p45
Gene Symbols MAP2K2
Host Species Goat
Immunogen Peptide with sequence C-DLKMLTNHTFIKRS (aa 359-372).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5605
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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