Invitrogen™ MEK2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIPA5119288	Invitrogen™ PA5119288	200 μL
PIPA5121787	Invitrogen™ PA5121787	20 μL

Description

MEK2 Polyclonal Antibody for Western Blot, ICC/IF

MAP2K2 (MEK2) is a dual specificity serine/threonine kinase that is known to play a critical role in mitogen growth factor signal transduction. Mitogen activated protein kinase 2 (MEK2 or MAPKK2) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1 and 2 and MAPK enzymes by phosphorylating both residues within the threonine/glutamate/tyrosine (TEY) motif in the activation loop. MEK1 and 2 are also activated by dual phosphorylation, which occurs on serine 218 and 222, in the activation loop of the MEK. Threonine 292 of MEK1 is phosphorylated by ERK 2, which serves as a negative feedback loop by suppressing activation of MEK1.

Specifications

• Antigen: MEK2
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Classification: Polyclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human, Rat, Bovine, Pig, Horse, Chicken
• Gene: MAP2K2
• Gene Alias: AA589381; CFC4; Dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 2; ERK kinase 2; FLJ26075; MAP kinase kinase 2; MAP kinase/Erk kinase; MAP2K1; MAP2K2; MAPK; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK 2; MAPKK2; MEK 1; MEK 2; MEK-1; Mek2; MEK-2; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; MK2; MKK1; Mkk2; OTTHUMP00000165827; PRKMK1; PRKMK2; protein kinase, mitogen activated, kinase 2, p45
• Gene Symbols: MAP2K2
• Primary or Secondary: Primary
• Purification Method: Antigen affinity chromatography, Protein A

• Concentration: 0.5 mg/mL
• Applications: Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: P36506, P36507, Q90891
• Gene ID (Entrez): 100063190, 100525505, 396349, 510434, 5605, 58960
• Immunogen: Recombinant protein Mitogen Activated Protein Kinase 2. The antigen corresponds to amino acid range 86-331 of the target protein.
• Product Type: Antibody