Invitrogen™ MEK5 Recombinant Rabbit Monoclonal Antibody (7B7O10)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA535172

Catalog No. PIMA535172

Description

Immunogen sequence: DVYRKMPEHV LGRIAVAVVK GLTYLWSLKI LHRDVKPSNM LVNTRGQVKL CDFGVSTQLV NSIAKTYVGT NAYMAPERIS GEQYGIHSDV WSLGISFMEL A.

MAP2K5 (MEK5) serine/threonine kinase (mitogen-activated protein kinase 5) or MEK5 is a dual specificity protein kinase that belongs to the MAP kinase family which specifically interacts with and activates MAPK7/ERK5. MAP2K5 itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by MAP2K5 is involved in growth factor stimulated cell proliferation and muscle cell differentiation. The rs3743354 polymorphism in the MAP2K5 promoter may affect the risk of developing colorectal cancer (CRC).

Specifications

• Antigen: MEK5
• Classification: Recombinant Monoclonal
• Concentration: 1.5 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q13163, Q62862, Q9WVS7
• Gene Symbols: MAP2K5
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 250-350 of human MEK5 (Q13163).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 7B7O10
• Conjugate: Unconjugated
• Gene: MAP2K5
• Gene Alias: AI324775; AI428457; Dual specificity mitogen-activated protein kinase kinase 5; HsT17454; MAP kinase kinase 5; MAP kinase kinase MEK5b; MAP2K5; MAPK/ERK kinase 5; MAPK/ERK kinese 5; MAPKK 5; Mapkk5; MEK 5; MEK5; mitogen activated protein kinase kinase 5; mitogen-activated protein kinase kinase 5; Mkk5; PRKMK5
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23938, 29568, 5607
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid