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Invitrogen™ MEK5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA582968

Catalog No. PIPA582968


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Description

Description

Immunogen sequence: LGRFPYPQIQ KNQGSLMPLQ LLQCIVDEDS PVLPVGEFSE PFVHFITQCM RKQPKERPAP EELMGHPFIV QFNDGNA.

MAP2K5 (MEK5) serine/threonine kinase (mitogen-activated protein kinase 5) or MEK5 is a dual specificity protein kinase that belongs to the MAP kinase family which specifically interacts with and activates MAPK7/ERK5. MAP2K5 itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by MAP2K5 is involved in growth factor stimulated cell proliferation and muscle cell differentiation. The rs3743354 polymorphism in the MAP2K5 promoter may affect the risk of developing colorectal cancer (CRC).
TRUSTED_SUSTAINABILITY
Specifications

Specifications

MEK5
Polyclonal
Unconjugated
MAP2K5
AI324775; AI428457; Dual specificity mitogen-activated protein kinase kinase 5; HsT17454; MAP kinase kinase 5; MAP kinase kinase MEK5b; MAP2K5; MAPK/ERK kinase 5; MAPK/ERK kinese 5; MAPKK 5; Mapkk5; MEK 5; MEK5; mitogen activated protein kinase kinase 5; mitogen-activated protein kinase kinase 5; Mkk5; PRKMK5
Rabbit
Antigen affinity chromatography
RUO
5607
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
0.8 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q13163
MAP2K5
Recombinant protein corresponding to Human MAP2K5. Recombinant protein control fragment (Product #RP-95209).
100 μL
Primary
Human
Antibody
IgG
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