Invitrogen™ MEKK2 Polyclonal Antibody

Catalog No.	Quantity
PIPA554443	100 μL

Catalog No. PIPA554443 Supplier Invitrogen™ Supplier No. PA554443

Description

Rabbit Polyclonal Antibody

Immunogen sequence: IAFGQSMDLH YTNNELVIPL TTQDDLDKAV ELLDRSIHMK SLKILLVING STQATNLEPL PSLEDLDNTV FGAERKKRLS IIGPTSRDRS SPPPGYIPDE LHQVARNGSF TSINSEGEFI PESMDQM Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.

MAP3K2 (MEKK2) is a serine/threonine kinase that activates kinases involved in the MAP kinase signaling pathway. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.

Specifications

• Antigen: MEKK2
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.4 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: Map3k2
• Gene Accession No.: Q9Y2U5
• Gene Alias: 2.7.11.25; 9630061B06Rik; AI585793; MAP/ERK kinase kinase 2; MAP3K2; MAPK/ERK kinase kinase 2; MAPKKK2; MEK kinase 2; MEKK 2; MEKK2; MEKK2B; mitogen activated protein kinase kinase kinase 2; mitogen-activated protein kinase kinase kinase 2; protein kinase MEKK2b
• Gene Symbols: Map3k2
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human MEKK2. Recombinant protein control fragment (Product #RP-102059).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10746
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG