Invitrogen™ MEKK4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120505

Catalog No. PIPA5120505

Description

Positive test controls include: K-562, Rat brain. Immunogen sequence: MREAAAALVP PPAFAVTPAA AMEEPPPPPP PPPPPPEPET ESEPECCLAA RQEGTLGDSA CKSPESDLED FSDETNTENL YGTSPPSTPR QMKRMSTKHQ.

This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.

Specifications

• Antigen: MEKK4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAP3K4
• Gene Alias: D17Rp17; D17Rp17e; dJ473J16.1 (mitogen-activated protein kinase kinase kinase 4); JNKK1; KIAA0213; MAP three kinase 1; MAP/ERK kinase kinase 4; MAP2K4; Map3k4; MAPK/ERK kinase kinase 4; MAPKKK4; MEK kinase 4; Mek4b; MEKK 4; MEKK4; mitogen activated protein kinase kinase kinase 4; mitogen-activated protein kinase kinase kinase 4; mKIAA0213; MTK1; predicted protein of HQ0412; PRKMK4; PRO0412; RP17; Rp17a; SAPK/ERK kinase 1; SERK1; SSK2/SSK22 MAP kinase kinase kinase, yeast, homolog of; Tas; T-associated sex reversal
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 308106, 4216
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.35 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q9Y6R4
• Gene Symbols: MAP3K4
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAP3K4 (NP_005913.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG