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Invitrogen™ MEKK4 Polyclonal Antibody
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Catalog No. PIPA5120505
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100 μL
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PIPA5120505 100 μL
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Catalog No. PIPA5120505 Supplier Invitrogen™ Supplier No. PA5120505
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Description

Rabbit Polyclonal Antibody

Positive test controls include: K-562, Rat brain. Immunogen sequence: MREAAAALVP PPAFAVTPAA AMEEPPPPPP PPPPPPEPET ESEPECCLAA RQEGTLGDSA CKSPESDLED FSDETNTENL YGTSPPSTPR QMKRMSTKHQ.

This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MEKK4
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1.35 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene MAP3K4
Gene Accession No. Q9Y6R4
Gene Alias D17Rp17; D17Rp17e; dJ473J16.1 (mitogen-activated protein kinase kinase kinase 4); JNKK1; KIAA0213; MAP three kinase 1; MAP/ERK kinase kinase 4; MAP2K4; Map3k4; MAPK/ERK kinase kinase 4; MAPKKK4; MEK kinase 4; Mek4b; MEKK 4; MEKK4; mitogen activated protein kinase kinase kinase 4; mitogen-activated protein kinase kinase kinase 4; mKIAA0213; MTK1; predicted protein of HQ0412; PRKMK4; PRO0412; RP17; Rp17a; SAPK/ERK kinase 1; SERK1; SSK2/SSK22 MAP kinase kinase kinase, yeast, homolog of; Tas; T-associated sex reversal
Gene Symbols MAP3K4
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAP3K4 (NP_005913.2).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 308106, 4216
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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