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Invitrogen™ MEKK4 Polyclonal Antibody
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Catalog No. PIPA552459
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100 μL
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PIPA552459 100 μL
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Catalog No. PIPA552459 Supplier Invitrogen™ Supplier No. PA552459
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KDREQRGQEN TSGFWLNRSN ELIWLELQAW HAGRTINDQD FFLYTARQAI PDIINEILTF KVDYGSFAFV RDRAGFNGTS VEGQCKATPG TKIVGYSTHH EHLQRQRVSF EQVKRIMELL EYIEALYPSL Q Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 85%.

This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MEKK4
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene MAP3K4
Gene Accession No. Q9Y6R4
Gene Alias D17Rp17; D17Rp17e; dJ473J16.1 (mitogen-activated protein kinase kinase kinase 4); JNKK1; KIAA0213; MAP three kinase 1; MAP/ERK kinase kinase 4; MAP2K4; Map3k4; MAPK/ERK kinase kinase 4; MAPKKK4; MEK kinase 4; Mek4b; MEKK 4; MEKK4; mitogen activated protein kinase kinase kinase 4; mitogen-activated protein kinase kinase kinase 4; mKIAA0213; MTK1; predicted protein of HQ0412; PRKMK4; PRO0412; RP17; Rp17a; SAPK/ERK kinase 1; SERK1; SSK2/SSK22 MAP kinase kinase kinase, yeast, homolog of; Tas; T-associated sex reversal
Gene Symbols MAP3K4
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MEKK4. Recombinant protein control fragment (Product #RP-89772).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4216
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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