Invitrogen™ MEKK6 Polyclonal Antibody

Catalog No.	Quantity
PIPA519182	100 μg

Catalog No. PIPA519182 Supplier Invitrogen™ Supplier No. PA519182

Description

Goat Polyclonal Antibody

This antibody is predicted to react with bovine, canine, human and mouse based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.

Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MEKK6 activates the JNK, but not ERK or p38 kinase pathways.

Specifications

• Antigen: MEKK6
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene: MAP3K6
• Gene Accession No.: O95382
• Gene Alias: apoptosis signal-regulating kinase 2; ASK2; map3k6; MAPKKK6; MEKK6; MGC125653; MGC20114; mitogen activated protein kinase kinase kinase 6; mitogen-activated protein kinase kinase kinase 6; OTTHUMP00000005063
• Gene Symbols: MAP3K6
• Host Species: Goat
• Immunogen: Synthetic peptide sequence (RAILAQRAGSTP) corresponding to the C-terminus amino acids of MAP3K6 (aa 1272-1283).
• Purification Method: Ammonium sulfate precipitation
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 313022, 9064
• Target Species: Human, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

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