MEL18 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-9249	100 μL

Catalog No. 50-198-9249 Supplier Bioss Supplier No. BS9673R

Description

Rabbit Polyclonal Antibody

The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.

Specifications

• Antigen: MEL18
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: PCGF2
• Gene Accession No.: P35227
• Gene Alias: DNA-binding protein Mel-18; MEL18; MEL-18; MGC10545; PCGF2; polycomb group ring finger 2; Polycomb group RING finger protein 2; RING finger protein 110; RNF110; Zinc finger protein 144; ZNF144
• Gene Symbols: PCGF2
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human MEL18.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7703
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG